Features

Gene Therapy Is Saving Children’s Lives — But Screening to Discover Who Needs It Is Lagging Behind | May 31, 2018

States have been slow to adopt newborn tests for genetic conditions. 

CRISPR Trials Are About to Begin in People — But We Still Don’t Know How Well It Works in Monkeys | April 11, 2018

Monkey studies look encouraging but show there’s still a lot to learn about the gene-editing technology.

AI Can Spot Signs of Alzheimer’s Before Your Family Does | March 19, 2018

Earlier diagnosis could help researchers develop drugs to slow the progress of the disease.

Gene-Altering Treatments Are Medicine’s Best Shot Yet Against Huntington’s Disease | Feb. 15, 2018

After 25 years, scientists are starting to make progress against the devastating illness.

CRISPR in 2018: Coming to a Human Near You | Dec. 18, 2017

The first clinical trials using the gene-editing technology are slated to begin in the U.S. and Europe.

FDA Vote Sets Stage for Gene Therapy’s Future  | Oct. 12, 2017

The first therapy that fixes an inherited genetic trait could soon be available in the U.S.

Why HPV Vaccination Rates Remain Low in Rural States | September 1, 2017
The potentially life-saving cancer vaccine has been around for more than a decade, so why isn’t everyone getting it?

Sickle Cell Patients See Hope in CRISPR Aug. 23, 2017

Long underserved by the medical establishment and Big Pharma, sickle cell disease is now being eyed for the first human tests of the gene-editing tool.

The Fertility Doctor Trying to Commercialize Three-Parent Babies | June 13, 2017

A startup called Darwin Life says it will use a controversial fertility technique to help forty-somethings get pregnant for $100,000.

A Year After Approval, a Gene-Therapy Cure Gets Its First Customer | May 3, 2017 

GlaxoSmithKline says it has treated a child with Strimvelis, its gene therapy for immune deficiency.

When Even Genome Sequencing Doesn’t Give a Diagnosis  | April 21, 2017

The technology has been touted as a powerful diagnostic tool, but it doesn’t provide answers to everyone.

Determined Parents Are Moving the Needle on Gene Therapy | March 21, 2017

Families of patients are starting advocacy groups, raising money for research, and founding biotech companies to advance cures for rare diseases.

17 and Going Blind: The High Stakes of Getting into a Gene Therapy Trial | Sept. 19, 2016

For patients with some inherited diseases, a chance to test an experimental treatment can offer the only hope.

News + Analysis

Before He Died, This Biohacker Was Planning a CRISPR Trial in Mexico | May 4, 2018

Aaron Traywick and his company, Ascendance Biomedical, are connected to a website advertising a gene-therapy trial for lung cancer.

Gene Therapy Could Free Some People from a Lifetime of Blood Transfusions | April 18, 2018
Correcting a genetic mutation lets beta thalassemia patients make healthy blood cells.

CRISPR May Not Cause Hundreds of Rogue Mutations After All | March 30, 2018
Researchers behind a controversial paper have admitted that their results may be wrong.

Fast Genome Tests Are Diagnosing Some of the Sickest Babies in Time to Save Them | March 8, 2018

Rapid DNA sequencing is helping doctors treat critically ill infants in days rather than weeks.

This New Company Wants to Sequence Your Genome and Let You Share It on a Blockchain | February 7, 2018
People will be able to earn cryptocurrency in exchange for letting pharma companies use their data.

A Cheap and Easy Blood Test Could Catch Cancer Early | January 18, 2018
50,000 healthy people will be screened in an effort to detect hidden tumors.

Still No Science Advisor at the White House | November 22, 2017
Science issues stack up as President Trump overlooks an appointment.

Men Will Soon Test a Sperm-Stopping Gel for Birth Control | Dec. 20, 2017

The gel might deliver hormones better than injections or pills.

Biohackers Disregard FDA Warning on DIY Gene Therapy | Dec. 1, 2017

The regulatory agency is cracking down on companies offering kits to produce gene therapies for self-administration.

Gene Editing Study in Human Embryos Points toward Clinical Trials | August 2, 2017
Researchers used CRISPR to correct a gene in embryos that causes sudden heart failure.

Do Your Family Members Have a Right to Your Genetic Code? | Nov. 22, 2016

When a woman gets her genome sequenced, questions about privacy arise for her identical twin sister.